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What is Sarcoidosis Disease?

What is Sarcoidosis Disease? | Senderra Specialty Pharmacy

Are you familiar with sarcoidosis? It's something that many people aren't aware of, yet it affects thousands of individuals throughout the world.

Sarcoidosis is an autoimmune related disease that leads to inflammation, usually in your lungs, skin, or lymph nodes and can affect any organ in your body.

In this blog post, we will cover what sarcoidosis is, the symptoms associated with it, treatments available, as well as general healthcare knowledge regarding living with this condition.

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What is Sarcoidosis Disease?

Sarcoidosis is an autoimmune, inflammatory disease that can occur anywhere in the body, from your lungs and lymph nodes to more unexpected places like eyes and heart. Granulomas form on affected organs as a result of this condition, leading to sometimes serious complications if left untreated.

The cause of sarcoidosis is unknown. Experts suspect that any combination of infectious agents, chemicals, dust and a potential abnormal reaction to the body's own proteins could be responsible for this disease in certain people who have an innate predisposition.

Symptoms of Sarcoidosis

Sarcoidosis can cause a variety of effects depending on which organs it targets. For some, sarcoidosis disease will gradually develop and see symptoms for many years, while others experience sudden symptoms and disappear just as quickly.

Many people with sarcoidosis have no symptoms, so the disease may be discovered only when a chest X-ray is done for another reason.

General Symptoms Eye Symptoms Heart Symptoms Lung Symptoms Skin Symptoms
Fatigue Blurred vision Chest pain Persistent dry cough A rash of red or reddish-purple bumps, usually located on the shins or ankles, which may be warm and tender to the touch
Swollen lymph nodes Eye pain Shortness of breath Shortness of breath Disfiguring sores (lesions) on the nose, cheeks and ears
Weight loss Burning, itching or dry eyes Fainting Wheezing Areas of skin that are darker or lighter in color
Pain and swelling in joints, such as the ankles Severe redness
Sensitivity to light
Fatigue Chest pain Growths under the skin (nodules), particularly around scars or tattoos
    Irregular heartbeats    
    Rapid or fluttering heart beat    
    Swelling caused by excess fluid    

 

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Types of Sarcoidosis

Symptoms for sarcoidosis vary, depending on the part of the body that is involved.

Pulmonary Sarcoidosis

Pulmonary sarcoidosis is the most common form of this condition, and it can have some uncomfortable symptoms. Granulomas in the lungs often result in shortness of breath, a cough, chest pain and fever.

Cardiac Sarcoidosis

Cardiac Sarcoidosis is a rare condition with potentially life-threatening consequences. Symptoms include fatigue, coughing, breathlessness and even dizziness in some cases, leading to heart failure or loss of consciousness if left untreated.

Skin Sarcoidosis

Skin sarcoidosis, also known as cutaneous sarcoidosis, occurs in nearly 25 to 30 percent of people and is more common among Black people. Symptoms can range from mild, with granulomas or lesions on the skin, to more severe, affecting a person’s quality of life and day-to-day activities.

Ocular Sarcoidosis

Ocular sarcoidosis affects the eyes, and symptoms depend on which part of the eye is affected. The most common part of the eye that's affected is the uveitis. Those symptoms include redness, inflammation, and pain in the eyes and nearby tissues.

Neurosarcoidosis

Sarcoidosis affects the nervous system in approximately 10 percent of people with sarcoidosis. Almost any part of the nervous system can be involved, including the brain and meninges, the spinal cord, facial and optic nerves, hypothalamus and the pituitary gland, peripheral nerves, and muscles.

Hepatic Sarcoidosis

Most people with hepatic sarcoidosis do not experience symptoms or require treatment because it does not usually affect the organ’s function.

Renal Sarcoidosis

Renal sarcoidosis affects the kidneys, and in some cases can result in kidney failure.

Sarcoidosis Affecting Other Organs

In rare cases, sarcoidosis can also affect the bones, stomach, and the reproductive organs.

Treatments for Sarcoidosis Disease

Although there is no cure for sarcoidosis, in many cases, it will go away on its own and may not require treatment. The severity and extent of your condition will determine if you need treatment and what type is needed.

Organ transplant may be considered if sarcoidosis has severely damaged your lungs, heart or liver.

Some medications include:

  • Corticosteroids may be administered topically as creams for skin lesions or drops in the eyes.
  • Medications that suppress the immune system, such as methotrexate (Trexall) and azathioprine (Azasan, Imuran) reduce inflammation.
  • Hydroxychloroquine (Plaquenil) may be helpful for skin lesions and elevated blood-calcium levels.
  • Tumor necrosis factor-alpha (TNF-alpha) inhibitors are commonly used to treat the inflammation associated with rheumatoid arthritis. They can also be helpful in treating sarcoidosis that hasn't responded to other treatments.

AutoImmune Disorder Specialty Pharmacy

In cases of immune system over activity, the body attacks and damages its own tissues (autoimmune diseases). Immune deficiency diseases decrease the body's ability to fight invaders, causing vulnerability to infections. 

Senderra offers specialized treatments for more than 15 specialties including autoimmune disorders, like rheumatoid arthritis, MS, and chronic asthma, gastroenterology, immune system disorders, dermatologic diseases, and more.

We put you first.

You deserve to be treated as a person, not a number.

With Senderra, you'll talk with real people who are dedicated to enabling you to get the medications and supporting information you need for your condition.

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About Senderra

Senderra-Logo_Mark-Only_COLOR-1Senderra is a national specialty pharmacy, serving patients with challenging and ongoing medical conditions, like autoimmune disorders, through provision of specialty medicationsclinical expertise and support services

We dedicate ourselves to designing and executing a model to serve the needs of our patients and partners (PrescribersPharma and Payers) in order to make a difference and effect positive outcomes. 


References:

Mayo Clinic

NYUL

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