Dermatologic Disorders Specialty Pharmacy
A Collection of Chronic Disorders Affecting the Skin
Dermatology is the branch of medicine that deals with skin, mucous membranes, hair and nails. Although relatively straightforward to examine, the skin is the largest organ and has numerous potential abnormalities - there are about 1500 distinct skin diseases and many variants. We are relatively ignorant about the pathogenesis of the majority of these although knowledge is rapidly increasing especially in the fields of immunology, molecular medicine and genetics.
Conditions
Alopecia Areata: Alopecia Areata (AA) is a common autoimmune disease of the skin which causes hair loss on the scalp, face, and other areas of the body. Alopecia areata affects 6.8 million people in the United States and has a lifetime risk of 2.1%. This disease affects people of all ages, sexes, and ethnicities.
Atopic Dermatitis: Atopic Dermatitis (AD) is the most common type of eczema. Atopic dermatitis affects nearly 10 million children and nearly 17 million adults in the United States. Atopic Dermatitis is a chronic autoimmune condition that triggers inflammation that causes damage to the skin barrier, resulting in dry, itchy rashes which may be discolored.
Hidradenitis suppurativa: Hidradenitis Suppurativa (HS) is a chronic skin condition characterized by swollen, painful lesions located in the armpit, groin, anal, and breast regions. The disease is caused by obstruction of hair follicles and secondary infection and inflammation of certain sweat glands. The disease is progressive in nature where boil-like abscesses filled with pus become hard and painful deep-seated clusters of lesions with chronic seepage.
Non-segmental Vitiligo: Non-Segmental Vitiligo is an autoimmune condition in which there are not enough working melanocyte skin cells producing melanin, which is the pigment that colors the skin. This causes white patches to develop on the skin and hair.
Prurigo Nodularis: Prurigo Nodularis (PN) is a rare inflammatory disease of the skin which causes raised, often severely itchy, bumps on the arms, legs, and trunk. There are approximately 88,000 new cases of Prurigo Nodularis each year in the United States. Although this disease can affect people of all ages, sexes, and ethnicities, elderly adults, women, individuals with HIV, and African Americans are affected at higher rates.
Psoriatic Arthritis: Psoriatic arthritis is a form of arthritis that is identified by red patches of skin topped with silvery scales. In most cases, psoriasis is developed first and later the psoriatic arthritis is a secondary diagnosis, however the joint problems can sometimes begin before skin lesions appear. Commonly, the joints that are affected include the hips, knees, and those closest to the tips of the fingers and toes. It resembles rheumatoid arthritis but does not produce the antibodies that are associated with rheumatoid arthritis. An increased risk is associated with those individuals that carry a certain gene (HLA-B27) or have family members that are affected by psoriatic arthritis.
Medications
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Adbry
ADBRY is a prescription medicine used to treat people 12 years and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. ADBRY can be used with or without topical corticosteroids.
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Cibinqo
CIBINQO is a prescription medicine that is a Janus Kinase (JAK) inhibitor. CIBINQO is used to treat people 12 years and older with moderate-to-severe atopic dermatitis (eczema) that did not respond to other treatment and is not well controlled with prescription therapies, including biologic medicines or when these medicines cannot be tolerated.
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Cimzia
CIMZIA is a prescription medication called a Tumor Necrosis Factor (TNF) blocker used to help patients with several autoimmune diseases including psoriatic arthritis as well as moderate to severe plaque psoriasis. CIMZIA works to achieve and maintain remission of psoriatic arthritis & plaque psoriasis by blocking one of the chemical messengers in the body associated with inflammation.
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Cosentyx
COSENTYX is a prescription medication used to help patients with several autoimmune diseases including psoriatic arthritis in adults and children 2 years of age and older, people 6 years of age and older with moderate to severe plaque psoriasis, and adults with moderate to severe hidradenitis suppurativa (HS). COSENTYX works to achieve and maintain remission of psoriatic arthritis, plaque psoriasis, and hidradenitis suppurativa by blocking one of the chemical messengers in the body associated with inflammation.
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Dupixent
DUPIXENT is an injectable prescription medication for the treatment of patients with moderate-to-severe atopic dermatitis (eczema) aged 6 months and older whose disease is not adequately controlled with topical prescription therapies. Dupixent is also used to treat adults with Prurigo Nodularis. It works by blocking one of the chemical messengers in the body associated with inflammation.
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Enbrel
ENBREL is a prescription medication called a Tumor Necrosis Factor (TNF) blocker used to help patients with several autoimmune diseases including psoriatic arthritis. ENBREL works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
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Eucrisa
EUCRISA is a prescription medicine used on the skin (topical) to treat mild to moderate eczema (atopic dermatitis) in adults and children 3 months of age and older.
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Humira
HUMIRA is a prescription medication called a Tumor Necrosis Factor (TNF) blocker used to treat several autoimmune and auto inflammatory disorders such as Hidradenitis Suppurativa in people aged 12 years and older. It works by blocking one of the chemical messengers in the body associated with inflammation.
HUMIRA is also used to treat adults with psoriatic arthritis. HUMIRA works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
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Olumiant
OLUMIANT is a Janus Kinase (JAK) inhibitor indicated for the treatment of adult patients with severe Alopecia Areata. It works by blocking one of the chemical messengers in the body associated with inflammation.
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Opzelura
OPZELURA is a prescription medicine used on the skin (topical) for short-term and non-continuous treatment of mild to moderate eczema (atopic dermatitis) in non-immunocompromised people age 12 and older whose disease is not well controlled with topical prescription therapies or when those therapies are not recommended.
Opzelura is also used to treat non-segmental vitiligo in adults and children ages 12 and older.
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Orencia
ORENCIA is a prescription medication used to help patients several autoimmune diseases, including adults with psoriatic arthritis. ORENCIA works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
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Otezla
OTEZLA is a prescription medication that is used to help patients with several autoimmune diseases including adults with psoriatic arthritis. OTEZLA works to achieve and maintain remission of psoriatic arthritis, and works by blocking one of the chemical messengers in the body associated with inflammation.
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Rinvoq
RINVOQ is a prescription medicine that is a Janus kinase (JAK) inhibitor. RINVOQ is used to treat adults and children 12 and older with moderate to severe eczema (atopic dermatitis) that did not respond to previous treatment and their eczema is not well controlled with other pills or injections, including biologic medicines, or the use of other pills or injections is not recommended.
RINVOQ is also used to treat adults with active psoriatic arthritis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
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Simponi
SIMPONI is a prescription medication used to help patients with several autoimmune diseases including adults with psoriatic arthritis. SIMPONI works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
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Simponi Aria
SIMPONI ARIA is a prescription medication used to help patients with several autoimmune diseases including patients age 2 years and older with psoriatic arthritis. SIMPONI ARIA works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
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Stelara
STELARA is a prescription medication used to help patients with several autoimmune diseases including adults and children ages 6 and older with psoriatic arthritis. STELARA works to achieve and maintain remission of psoriatic arthritis, and works by blocking one of the chemical messengers in the body associated with inflammation.
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Taltz
TALTZ is a prescription medication used to help patients with several autoimmune diseases including psoriatic arthritis. TALTZ works to achieve and maintain remission of psoriatic arthritis, and works by blocking one of the chemical messengers in the body associated with inflammation.
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Tremfya
TREMFYA is a prescription medication used to help patients with several autoimmune diseases including adults with psoriatic arthritis. TREMFYA works to achieve and maintain remission of psoriatic arthritis, and works by blocking one of the chemical messengers in the body associated with inflammation.
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Xeljanz
XELJANZ/XELJANZ XR is a prescription medication used to help patients with several autoimmune diseases including adults with psoriatic arthritis. XELJANZ/XELJANZ XR works to achieve and maintain remission of psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.