Rheumatologic Disorders Specialty Pharmacy
Rheumatologic disorders are autoimmune and inflammatory disorders that cause your immune system to attack your joints, muscles, bones and organs
Rheumatologic disorders can cause damage to your vital organs, including the lungs, heart, nervous system, kidneys, skin and eyes. Rheumatologic diseases may result in conditions so severe that those who suffer from them cannot bathe or dress themselves. Additionally, a simple task such as walking can cause pain and be difficult or even impossible.
Conditions
Systemic Lupus Erythematosus: Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. There is no cure for lupus, but medical interventions and lifestyle changes can help control it.
Myositis: Myositis refers to any condition causing inflammation in muscles. Weakness, swelling, and pain are the most common myositis symptoms. Myositis causes include infection, injury, autoimmune conditions, and drug side effects. Treatment of myositis varies according to the cause.
Juvenile Idiopathic Arthritis: Juvenile Idiopathic Arthritis is a group of related childhood diseases that begin by age 16 and involve persistent or recurring inflammation of the joints. Juvenile idiopathic arthritis may also affect other organs or connective tissue. JIA is not the same thing as adult Rheumatoid Arthritis, although there are similarities.
Psoriatic Arthritis: Psoriatic arthritis is a spondyloarthritis and a form of joint inflammation that occurs in some people who have psoriasis of the skin or nails. The joints commonly involved are the fingers, hips, knees, and toes. Psoriatic arthritis is similar to rheumatoid arthritis but does not produce antibodies characteristic of RA. Psoriatric arthritis occurs in about 30% of people with psoriasis. People who have a certain gene (HLA-B27) and those who have family members affected by this gene may have increased risk for psoriatic arthritis of the spine. There is no cure for psoriatic arthritis, however, there are several treatments available in the form of disease modifying anti-rheumatic drugs (DMARDs), Tumor Necrosis Factor inhibitors (TNFs), and other biologic agents.
Behcet's Disease: Behcet's disease is a chronic blood vessel inflammation (vasculitis) that can cause painful mouth and genital sores, skin lesions, and eye problems. Inflammation can also occur in the joints, nervous system, and digestive tract. Sores can appear, disappear, and reappear in the mouth, on the genitals, and skin. Specific treatment well depend on what areas are affected, but usually involves corticosteroids, immunosuppressants, and other DMARDs.
Medications
-
Actemra
ACTEMRA is a prescription medication used to help patients with several autoimmune diseases including juvenile idiopathic arthritis in ages 2 and older. ACTEMRA works to achieve and maintain remission of juvenile idiopathic arthritis, and works by blocking one of the chemical messengers in the body associated with inflammation.
-
Acthar Gel
Acthar Gel is a prescription medicine used for the treatment of several autoimmune disorders. Acthar is believed to work by helping your body produce its own natural steroid hormones. Natural steroid production helps your body regulate inflammation. Acthar is not a steroid. Acthar is a self-injectable medication that provides a prolonged release of the medication after it is injected.
-
Benlysta
BENLYSTA is used to treat systemic lupus erythematosus (SLE), in patients who are receiving other lupus medicines. It works by binding to a protein (found in high levels in patients with active lupus) in the blood and limiting the activity of the protein. It helps decrease the symptoms of lupus.
-
Cosentyx
COSENTYX is a prescription medication used to treat several autoimmune disorders including psoriatic arthritis in ages 2 and older as well as active enthesitis-related arthritis (ERA) (a subtype of Juvenile Idiopathic Arthritis) in patients 4 and older. COSENTYX works to achieve and maintain remission of JIA and psoriatic arthritis & works by blocking one of the chemical messengers in the body associated with inflammation.
-
Enbrel
ENBREL is a prescription medication called a Tumor Necrosis Factor (TNF) blocker used to help patients with several autoimmune diseases including moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. ENBREL works to achieve and maintain remission of JIA & works by blocking one of the chemical messengers in the body associated with inflammation.
-
Humira - JIA
HUMIRA is a prescription medication called a Tumor Necrosis Factor (TNF) blocker used to help patients with several autoimmune diseases including moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. HUMIRA works to achieve and maintain remission of JIA & works by blocking one of the chemical messengers in the body associated with inflammation.
-
Hyrimoz - (JIA)
HYRIMOZ® (adalimumab-adaz) is a prescription medicine called a tumor necrosis factor (TNF) blocker used:
- To reduce the signs and symptoms of:
- Moderate to severe rheumatoid arthritis (RA) in adults. HYRIMOZ can be used alone, or with methotrexate, or with certain other medicines. HYRIMOZ may prevent further damage to your bones and joints and may help your ability to perform daily activities
- Moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years of age and older. HYRIMOZ can be used alone or with methotrexate
- Psoriatic arthritis (PsA) in adults. HYRIMOZ can be used alone or with certain other medicines. HYRIMOZ may prevent further damage to your bones and joints and may help your ability to perform daily activities
- Ankylosing spondylitis (AS) in adults
- Moderate to severe hidradenitis suppurativa (HS) in adults
- To reduce the signs and symptoms of:
-
Idacio
IDACIO® (adalimumab-aacf) is an FDA-approved biosimilar to Humira® (adalimumab) that addresses patients’ and prescribers’ core needs.1
First approved in 2019, and already available in nearly 40 countries around the world, IDACIO is indicated for:
- Moderate to severe rheumatoid arthritis in adults
- Moderate to severe polyarticular juvenile idiopathic arthritis in children age 2 years or older
- Psoriatic arthritis in adults
- Ankylosing spondylitis in adults
- Moderate to severe Crohn’s disease in adults and children 6 years of age or older
- Moderate to severe chronic plaque psoriasis in adults
- Moderate to severe ulcerative colitis in adults
- Moderate to severe hidradenitis suppurativa in adults
- Non-infectious intermediate, posterior, and panuveitis in adults
-
Orencia - JIA
ORENCIA is a prescription medication used to help patients with several autoimmune diseases, including patients ages 2 and older with moderate to severe polyarticular juvenile idiopathic arthritis (JIA). ORENCIA works to achieve and maintain remission of JIA & works by blocking one of the chemical messengers in the body associated with inflammation.
-
Simlandi - (JIA)
SIMLANDI is a medicine called a tumor necrosis factor (TNF) blocker
SIMLANDI is given by injection under the skin. SIMLANDI is used to reduce the signs and symptoms of:
- moderate to severe rheumatoid arthritis (RA) in adults. SIMLANDI can be used alone, with methotrexate, or with certain other medicines.
- moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years and older. SIMLANDI can be used alone or with methotrexate.
- psoriatic arthritis (PsA) in adults. SIMLANDI can be used alone or with certain other medicines.
- ankylosing spondylitis (AS) in adults.
- moderate to severe hidradenitis suppurativa (HS) in adults.
- To treat moderate to severe Crohn’s disease (CD) in adults and children 6 years of age and older.
- To treat moderate to severe ulcerative colitis (UC) in adults. It is not known if adalimumab products are effective in people who stopped responding to or could not tolerate anti-TNF medicines.
- To treat moderate to severe chronic plaque psoriasis (Ps) in adults who have the condition in many areas of their body and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills)
- To treat non-infectious intermediate, posterior, and panuveitis in adults.
-
Simponi Aria - JIA
SIMPONI ARIA is a prescription medication used to help patients with several autoimmune diseases, including patients ages 2 and older with polyarticular juvenile idiopathic arthritis (JIA). SIMPONI ARIA works to achieve and maintain remission of JIA & works by blocking one of the chemical messengers in the body associated with inflammation.
-
Xeljanz - JIA
XELJANZ is a prescription medication used to help patients with several autoimmune diseases, including patients ages 2 and older with polyarticular juvenile idiopathic arthritis (JIA). XELJANZ works to achieve and maintain remission of JIA & works by blocking one of the chemical messengers in the body associated with inflammation.